This course introduces the principles of Genetics, Mendelian and non-Mendelian inheritance, elucidates nucleic acids as genetic material of living organisms and role of epigenetics in conjunction with structure and function of genes, chromatin, chromosomes, and genomes. The concept and health implications of population genetics will be discussed. Topics on genetic disorders and cancer genetics will be covered to exemplify the role of genetic mutations in human disease and susceptibility. Evolution of recombinant DNA technologies Next Gen sequencing technology and their applications in multiple avenues related to human and planetary health will be covered. The students will be introduced to DNA and RNA modifying enzymes, and how they are used in PCR (end-point and real time), cloning, and gene editing technologies and other modifications to engineer recombinant DNA molecule, genomic/cDNA and engineered libraries and their applications in human and planetary health. This course examines the evolution of recombinant proteins, monoclonal antibodies, vaccines, and cell and gene therapies within the contemporary healthcare landscape. It explores recent advances in these technologies, their impact on biomedical innovation, and the opportunities for improving their effectiveness, accessibility, and affordability to address global healthcare needs.