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Dr. Arshdeep Sidhu
Current Position
Visiting Faculty, Plaksha University
Education
Ph.D. in Nanobiophysics, University of Twente, The Netherlands
Research Interests:
· Intrinsically disordered proteins
· Protein self-assembly in pathological aggregates and membraneless organelles
· Biomarkers for Parkinson’s disease
· Protein based materials
· Single molecule imaging
Past Associations:
· Assistant Professor, Department of Molecular Genetics and Cancer, Nitte University, Mangalore, India.
· Post-doctoral fellow, Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
· Research scholar, NMR lab, National Institute of Immunology, New Delhi, India.
Bio
Dr Arshdeep Sidhu is a protein biochemist with a specialization in single molecule/conformation imaging using atomic force microscopy. Her research interest includes studying conformation-function of intrinsically disordered proteins and to develop protein-based materials for diverse applications.
She did her PhD from University of Twente, The Netherlands, where she studied polymorphism and functionalization of a Parkinson’s disease associated protein – α-Synuclein. During her postdoctoral fellowship at Erasmus Medical Centre, Rotterdam, she studied the conformation-function relation of BRCA2 protein – a protein associated with breast cancer.
As an assistant professor at Nitte University, Mangalore her group developed model systems to study phase separation behaviour of intrinsically disordered proteins. She is passionate about developing physiologically relevant in-vitro model systems that will enable single molecule studies of DNA repair foci and liquid to solid transition of amyloidogenic proteins. These model systems can be valuable tools to annotate clinical variants and guide clinical decision for age-associated diseases like cancer and neurodegeneration.
In addition to her research interests, Arshdeep likes to travel, learn new skills and is an environmentalist, who actively seeks and implements solutions for everyday sustainable living.